Rabbit Anti-Ezh1 (Enhancer of Zeste Homolog 1, ENX-2, KIAA0388, Polycomb group (PcG) Protein)
EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z), a member of the polycomb group of transcriptional repressors. In mice, EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. The strong sequence conservation between species suggests potential role for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that stably maintain heterochromatin.
Applications
Suitable fro use in Western Blot. Other applications have not been tested.
Recommended Dilution
Western blot: 2-4ug/ml Optimal dilutions to be determined by the researcher.
Recommended Positive Control
Human or mouse spleen
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
A portion of aa350-400 of human EZH1. Species sequence homology: mouse 93%, rat and canine 86%.
Form
Supplied as a liquid in PBS, 0.05% BSA, 0.02% sodium azide.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human EZH1. Species crossreactivity: mouse.
