FLI1 is a member of ETS family of transcription factors and is a proto-oncogene involved in erythroleukemia and Ewings sarcoma. FLI1 was originally identified as a common proviral insertion (Friend leukemia insertion site 1) and found in 75% of erythroleukemia cell clones induced by the Friend mouse leukemia virus. A chromosomal translocation between the FLI1 gene and EWS gene is found in most Ewing sarcomas. FLI1 has anti-apoptotic acivities and also interferes with nuclear hormone receptors.

Suitable for use in FLISA and Western Blot. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

FLI1 (AAH01670, 1-453aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.

Purified.

Recognizes human FLI1. Species Crossreactivity: rat.