Rabbit Anti-GLUT 5 (Glucose Transporter 5, Glucose Transporter Type 5 Small Intestine, GLUT5, GLUT-5, Fructose Transporter, Solute Carrier Family 2 Facilitated Glucose Transporter Member 5, SLC2A5)
Glucose 5 transporter catalyses the uptake of D-fructose into cells. This 55kD protein is expressed in the plasma membrane and is found mainly in intestinal tissue, kidney, and spermatozoa. Increased intestinal levels of GLUT5 are seen in type 2 diabetes
Applications
Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested.
Recommended Dilution
Immunohistochemistry (paraffin): 1:50-1:200 Western Blot: 1:150-1:500 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
A synthetic peptide (ELKELPPVTSEQ) corresponding to the carboxy terminus of the Human GLUT 5. To accomodate KLH conjugation a cysteine was added to the N-terminal.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Glucose Transporter 5. Does not crossreact with mouse or rat.
