Technical Data

G8603-51A
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_689414.1
Gene ID
83756
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-TAS1R3 (Taste Receptor Type 1 Member 3, Sweet Taste Receptor T1R3, T1R3, TR3)

Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-QGQNDGNTGNQGKHE, from TAS1R3, at the internal region of the protein (NP_689414.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes TAS1R3. Species sequence homology: Human.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Damak S, Rong M, Yasumatsu K, Kokrashvili Z, Varadarajan V, Zou S, Jiang P, Ninomiya Y, Margolskee RF. Detection of sweet and umami taste in the absence of taste receptor T1r3. Science. 2003 Aug 8;301(5634):850-3.
USBio References
No references available
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