Technical Data

H1830-13
Clone Type
Polyclonal
Host
Goat
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-Heartworm, Canine (Dirofilaria immitis)

Heartworm is a parasitic roundworm (Dirofilaria immitis) that is spread from host to host through the bites of mosquitoes. The heartworm is a type of filaria, a small thread-like worm. The definitive host is the dog but it can also infect cats, wolves, coyotes, foxes and other animals, such as ferrets, sea lions and even, under very rare circumstances, humans. The parasite is commonly called 'heartworm' because the adult reproductive stage of its life cycle resides primarily in the right ventricle of its host where it can live for many years. Heartworm infection may result in serious disease for the host. Heartworms go through several life stages before they become adults infecting the heart of the host animal. The worms require the mosquito as an intermediate stage in order to complete their life cycle. Development in the mosquito is temperature dependent, requiring approximately two weeks of temperature at or above 27°C. Below a threshold temperature of 14°C, development cannot occur, and the cycle will be halted. As a result, transmission is limited to warm months, and duration of the transmission season varies geographically. The period between the initial infection when the dog is bitten by a mosquito and the maturation of the worms into adults living in the heart takes 6 to 7 months in dogs and is known as the 'prepatent period'.

Applications
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Heartworm Dirofilaria immitis
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified
Specificity
Recognizes Heartworm (Dirofilaria immitis).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
http://en.wikipedia.org/wiki/Dirofilaria_immitis
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net