Rabbit Anti-HLA Class 2 Antigen DRA, CT (HLA Class II Histocompatibility Antigen DR alpha Chain, HLA-DRA, HLA-DRA1, FLJ51114, MHC Class II Antigen DRA, MLRW)
Major Histocompatibility Complex, Class II, DR alpha
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).
Applications
Suitable for use in ELISA, Western Blot, and Indirect Flow Cytometry. Other applications not tested.
Recommended Dilution
Western Blot: 1:50-1:100 ELISA: 1:1,000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the C-terminal region of human HLA-DRA (KLH).
Form
Supplied as a liquid in PBS, 0.44% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human HLA-DRA.
