Technical Data

H6285-28C
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu Mk Mo Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-hnRNP K (Heterogeneous Nuclear Ribonucleoprotein K, hnRNPK, HNRPK, dC Stretch Binding Protein, CSBP, FLJ41122, Transformation Up-regulated Nuclear Protein, TUNP)

hnRNPK is most extensively studied among heterogeneous nuclear ribonucleoprotein families which plays an important role in cell signaling, telomere elongation, DNA repair and regulation of expression at both transcriptional and translational levels. It is a highly conserved RNA:DNA-binding protein which interacts with different classes of factors of extracellular signals.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 2-5ug/ml Optimal dilutions to be determined by the researcher.
Positive Control
K562 (human) and NIH 3T3 (mouse) cell lysate
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa200-250 of human hnRNPK.
Form
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human hnRNPK. Species Crossreactivity: chimpanzee, monkey, mouse, rat, opossum. Species sequence homology: chicken and canine.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Mikula, M. et al. Proteomics. 6:2395-2406 (2006). 2. Bomsztyk, K. et al. Bioessays. 26:629-638 (2004).
USBio References
No references available
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