Technical Data

I7654-92
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_060023.1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-INO80 (INO80 Homolog (S. cerevisiae))
homolog of yeast INO80, INO80 complex subunit A, INO80 complex homolog 1, hINO80, INOC1, INO80A, INO80 homolog (S. cerevisiae), INO80

The protein encoded by this gene represents the catalytic ATPase subunit of the INO80 chromatin remodeling complex. This complex binds DNA and is recruited by YY1 to activate certain genes.

Applications
Suitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:4000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-TQEDYDSNHFKAQ, from the internal region of human INO80 NP_060023.1.
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes INO80. Species sequence homology: human, rat, canine, bovine.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Yao T, Song L, Jin J, Cai Y, Takahashi H, Swanson SK, Washburn MP, Florens L, Conaway RC, Cohen RE, Conaway JW.Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Molecular cell 2008 Sep 31 (6): 909-17.
USBio References
No references available
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