Technical Data

I8440-03R
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_003844.1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-IL18RAP, NT (CD218b, CDw218b, CD218 Antigen-like Family Member B, Interleukin-1 Receptor 7, IL-1R-7, IL-1R7, Accessory Protein-like, AcPL, IL-1R Accessory Protein-like, IL-1RAcPL, Interleukin-18 Receptor beta, IL-18R-beta, IL-18Rbeta, Interleukin-18 Receptor Accessory Protein-like, Interleukin-18 Receptor Accessory Protein, IL-18 Receptor Accessory Protein, IL-18RAcP, IL1R7)

IL18RAP is required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.

Applications
Suitable for use in ELISA, Immunohistochemistry, Indirect Flow Cytometry and Western Blot. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect FLow Cytomtry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 73-101 in the N-terminal region of human IL18RAP
Form
Supplied as a liquid in PBS, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human IL18RAP

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Debets R., et.al., J. Immunol. 165:4950-4956(2000).
USBio References
No references available
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