Technical Data

L1662-96C
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_066277; O75610
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Lefty B, CT (Left-Right Determination Factor B, LEFTB, LEFTYB, Left-right Determination Factor 1, LEFTY1, Protein Lefty-1, Protein Lefty-B, UNQ278/PRO317)

LEFTB is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products.

Applications
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide at the C-term of human LEFTB (KLH).
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human LEFTB.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Kosaki K.,Am. J. Hum. Genet. 64:712-721(1999). 2.Dvash,T.,Stem Cells 25(2), 465-472 (2007). 3.Besser,D.,J. Biol. Chem. 279(43), 45076-45084 (2004).
USBio References
No references available
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