Technical Data

L2198-75B-APC
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
APC
Isotype
IgG
Grade
Affinity Purified
Applications
IHC
Crossreactivity
Hu
Accession #
NP_004780.1
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
BSA Free
Rabbit Anti-LIM Homeobox 2 (LHX2, hLhx2, Homeobox Protein LH2, LH2, LIM HOX Gene 2, MGC138390) (APC)

LIM homeobox 2, also known as LHX2, is a gene that belongs to the LIM homeobox family. These genes seem to play an important role in asymmetric cell division, tissue specification and differentiation of specific cell types. LHX2 is expressed in developing B-cells, the forebrain, liver, during embryonic development when limbs and organs are developing, in the optic stalk, and olfactory epithelia. Studies have shown that under-expression of LHX2 during embryonic development causes hepatic fibrosis.

Applications
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry: 1:100-500 Optimal dilutions to be determined by the researcher.
Positive Control
Human hippocampal and mouse cerebellum tissue
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Linear peptide selected from residues of human LHX2 (KLH). Species sequence homology: equine, canine, bovine (93%); mouse (80%).
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human LHX2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Richter, K., et al. (2003). Haematologica. 88:1336-1347. 2. Wandzioch, E., et al. (2004). PNAS. 101(47):16549–16554.
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net