Rabbit Anti-LIM Homeobox 2 (LHX2, hLhx2, Homeobox Protein LH2, LH2, LIM HOX Gene 2, MGC138390)
LIM homeobox 2, also known as LHX2, is a gene that belongs to the LIM homeobox family. These genes seem to play an important role in asymmetric cell division, tissue specification and differentiation of specific cell types. LHX2 is expressed in developing B-cells, the forebrain, liver, during embryonic development when limbs and organs are developing, in the optic stalk, and olfactory epithelia. Studies have shown that under-expression of LHX2 during embryonic development causes hepatic fibrosis.
Applications
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry: 1:100-500 Optimal dilutions to be determined by the researcher.
Positive Control
Human hippocampal and mouse cerebellum tissue
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Linear peptide selected from residues of human LHX2 (KLH). Species sequence homology: equine, canine, bovine (93%); mouse (80%).
Form
Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human LHX2.
