Technical Data

L7500-27C
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_000885
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Luteinizing Hormone, beta, CT (Luteinizing Hormone Subunit beta, LHB, LH-B, hLHB, LSH-beta, LSH-B, CGB4, Lutropin beta Chain, Lutropin Subunit beta)
Luteinizing Hormone beta Polypeptide, Luteinising Hormone

LHB is a member of the glycoprotein hormone beta chain family and is the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

Applications
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 78-104 in the C-terminal region of human Luteinizing Hormone, beta. UniProt Accession # P01229.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human Luteinizing Hormone, beta.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Lofrano-Porto,A., N. Engl. J. Med. 357(9), 897-904 (2007). 2.Liu,S., Endocr. J. 52(6), 781-784 (2005). 3.Keutmann,H.T., Mol. Endocrinol. 6(6), 904-913 (1992).
USBio References
No references available
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