Technical Data

M1253
Clone Type
Polyclonal
Host
Rabbit
Source
Rat
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Mo Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Mpg-1 (Macrophage Specific Gene, MSG, MPS1)

Mpg-1 (macrophagespecific gene, MSG, MPS1) is originally cloned from a macrophage cDNA library. Transcripts of Mpg-1 are found at a high level in mature human and murine macrophages and at a moderate level in certain myelomonocytic cell lines. Mpg-1-specific transcript was not detected in a wide variety of other tissues and cell lines. The predicted 669-amino acid Mpg-1-encoded protein has potential glycosylation and phosphorylation sites in addition to a signal sequence. The predicted molecular weight of the core protein is 71 to 74kD. Mpg-1 may share a distant ancestry to perforin. The function of Mpg-1 is unknown.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
E. coli-expressed rat Mpg-1
Form
Supplied as a liquid, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes rat Mpg-. Species crossreactivity: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Spilsbury, K. et al. (1995) Isolation of a novel macrophage-specific gene by differential cDNA analysis. Blood 85: 1620-1629.
USBio References
No references available
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