Technical Data

M2350-02C
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_114033
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MAP2, CT (Microtubule Associated Protein 2, MAP-2)

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The exact function of this gene is still unknown. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development.

Applications
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1766-1796 in the C-terminal region of human MAP2, Swiss/UniProt Accession #: P11137|
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human MAP2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Lauckner, J., et al., Neurobiol. Aging 24(6):767-776 (2003). 2.Laurine, E., et al., J. Biol. Chem. 278(32):29979-29986 (2003). 3.Liu, Y., et al., Adv Anat Pathol 10(2):101-106 (2003). 4.DeTure, M.A., et al., J. Biol. Chem. 277(38):34755-34759 (2002). 5.Al-Bassam, J., et al., J. Cell Biol. 157(7):1187-1196 (2002).
USBio References
No references available
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