Technical Data

M2871-10G
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_005950.1
Gene ID
4544
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-MTNR1B (Melatonin Receptor Type 1B, Mel-1B-R, Mel1b Receptor)

High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:32,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-QDASKGSHAEGLQSP, from MTNR1B, at C-terminal (NP_005950.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes MTNR1B. Species sequence homology: Human.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Rawashdeh O, de Borsetti NH, Roman G, Cahill GM. Melatonin suppresses nighttime memory formation in zebrafish. Science 2007 Nov 318(5853):1144-6.
USBio References
No references available
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