Rabbit Anti-Natriuretic Peptide, C-Type (1-29) (CNP-53, CNP) (Not for Export EU)
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.
Applications
Suitable for use in Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended Dilutions
Immunofluorescence: 1:200 Immunohistochemistry (formalin-fixed paraffin): 1:500 (ABC, DAB) Optimal dilutions to be determined by the researcher.
Amino Acid Sequence
Asp-Leu-Arg-Val-Asp-Thr-Lys-Ser-Arg-Ala-Ala-Trp-Ala-Arg-Leu-Leu-His-Glu-His-Pro-Asn-Ala-Arg- Lys-Tyr-Lys-Gly-Gly- Asn
Positive Control
Mouse and Rat Heart tissue, Rat Kidney tissue
Storage and Stability
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Synthetic peptide corresponding to aa1-29 of rat CNP-53.
Form
Supplied as a lyophilized powder. Reconstitute with 50ul of sterile dH2O.
Specificity
Recognizes rat CNP-53. Species Crossreactivity: mouse and porcine
