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O8251-04B Goat Anti-Oxytocin Receptor (OTR, OT-R, OTR1, OXTR)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_000907.2
Shipping Temp
Blue Ice
Storage Temp
-20°C

The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are also present in the central nervous system. These receptors modulate a variety of behaviors, including stress and anxiety, social memory and recognition, sexual and aggressive behaviors, bonding (affiliation) and maternal behavior. In some mammals, oxytocin receptors are also found in the kidney and heart.

Applications
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry . Other applications not tested.
Recommended Dilutions
ELISA (Peptide): 1:64,000 Western Blot: 2ug/ml Immunohistochemistry (Paraffin): 8ug/ml used human ovary Flow Cytometry: 1ug/ml using Jurkat cells Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Syntehtic peptide corresponding to C-LRTTRQKHSRL at the internal region of human OXTR.
Form
Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human OXTR.
References
1. Windle, R.J., et al., Endocrinology 147: 2423-2431 (2006).
USBio References
No references available
Conjugates
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