Technical Data

P3048-73
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_078870
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Pantothenate Kinase 3 (Pantothenic Acid Kinase 3, PANK3, hPanK3)
EC=2.7.1.33

PANK3 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.

Applications
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the Center region of human PANK3 (KLH).
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Recognizes human PANK3.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Zhou, B., et al., Nat. Genet. 28(4):345-349 (2001). 2.Robishaw, J.D., et al., Am. J. Physiol. 248(1 PT 1), E1-E9 (1985).
USBio References
No references available
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