Rabbit Anti-RhoGap12 (Rho GTPase-activating Protein 12, Rho-type GTPase-activating Protein 12, ARHGAP12) (Not for Export EU)
RhoGap12 encodes a potent Rho GTPase-activating protein. The protein is ubiquitously expressed in wide range of normal tissues and tumor cell lines. The protein contains five domains: rhoGAP, SH3, PH and two WW domains. Human RhoGap12 gene is located in chromosome 10pter-cen and consists of 20 exons. The protein acts as a linker between Rho signal pathways and other pathways.
Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa40-56 (ILVKKTNDDWWQVKPD) of human RhoGap12.
Form
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity
Recognizes human RhoGap12. Species Crossreactivity: monkey. Species sequence homology: mouse.
