Technical Data

S0048-50
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_002959.2; NP_001121364.1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-SALL1 (aa29-43)(Spalt-like Transcription Factor 1, sal-like 1, ZNF794, TBS, HSAL1, sal-like 1 (Drosophila), SALL1)
spalt-like transcription factor 1, sal-like 1, ZNF794, TBS, HSAL1, sal-like 1 (Drosophila), SALL1

The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:32,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to EKGQPSRPTKSKDAH-C, from the N-Terminus of human SALL1 (NP_002959.2; NP_001121364.1).
Form
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes both isoforms of SALL1. (NP_002959.2; NP_001121364.1). Species sequence homology: human and mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Barry JS, Reddy MAThe association of an epibulbar dermoid and Duane syndrome in a patient with a SALL1 mutation(Townes-Brocks Syndrome).Ophthalmic Genet. 2008 Dec;29(4):177-80
USBio References
No references available
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