Mouse Anti-SIK2 (Serine/Threonine-protein Kinase SIK2, Qin-induced Kinase, Salt-inducible Protein Kinase 2, SIK-2, Serine/Threonine-protein Kinase SNF1-like Kinase 2, KIAA0781, QIK, SNF1LK2)
SIK2 (Salt inducible kinase 2) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and AMP-activated protein kinase (AMPK) subfamily, predicted molecular weight 104kD. SIK2 is found in adipocytes and might be involved in metabolic regulation in adipose tissue. Sik2 phosphorylates ser794 of human insulin receptor substrate-1 (IRS1) in insulin-stimulated adipocytes, playing important roles in modulating the insulin-signaling cascade of adipocytes.
Applications
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilutions
Western Blot: 1:250 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein corresponding to human SIK2
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by affinity chromatography
Specificity
Recognizes human SIK2
