Rabbit Anti-Somatostatin (SMST, SST, Growth Hormone Release-inhibiting Factor)
Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF) is widely distributed throughout the body. It has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids. Somatostatin is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid.
Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Synthetic peptide corresponding to human Somatostatin.
Form
Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Specificity
Recognizes human Somatostatin. Species crossreactivity: Somatostatin (rat, mouse, porcine), Somatostatin-28, Somatostatin-25. % Cross-reactivity with Peptides: Somatostatin: 100%; Somatostatin-28: 100%; Somatostatin-25: 100%; [D-Trp8]-Somatostatin: 0%; Pro-Somatostatin-32: 0%; Somatostatin Analog, RC-160: 0%; Somatostatin Analog (CTOP): 0%; Insulin (Human): 0%; Glucagon (Human): 0%; Amylin (Human): 0%
