Technical Data

S5353-02B
Clone Type
Polyclonal
Host
Mouse
Source
Human
Isotype
IgG
Grade
Serum
Applications
E WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-SorCS2 (Sortilin-related VPS10 domain containing receptor 2, KIAA1329, VPS10 domain-containing receptor SorCS2 precursor) (Not for Export EU)

SorCS2 is a family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. It is noted that all mammalian VPS10 domains carry an N-terminal signal peptide for translocation into the endoplasmic reticulum. The greatest similarity between the receptors is found in the C-terminal parts of the VPS10 domains, which harbor 12 cysteine residues with a characteristic spacing conserved in all VPS10 proteins from yeast to man. SorCS2 is a single-pass type I membrane protein that is highly expressed in brain and kidney. It is also detected at low levels in heart, liver, small intestine, skeletal muscle and thymus.

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Partial recombinant human SorCS2 (951-1050) with a GST tag.
Form
Supplied as a liquid in 50% glycerol.
Purity
Serum
Specificity
Recognizes human SorCS2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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