Rabbit Anti-Tumor Necrosis Factor Receptor 2, p75/p80 (TNFR 2, Tnfr2, Tnfr-2, TNF-R2, Tumor Necrosis Factor Receptor Type II, TNFRII, TNFR-II, TNF-RII, TNF-R-II, CD120b, p75, p80 TNF alpha Receptor, TNF-R75, TNFR80, TNFalpha-R2, TNF-alphaR2, Tumor Necrosis Factor beta Receptor, TNFBR, Tumor Necrosis Factor Receptor Superfamily Member 1B, TNFRSF1B, TNFR1B)
Etanercept, p75TNFR, Soluble TNFR1B Variant 1, Tumor Necrosis Factor Binding Protein 2, TBP2, TBPII, Tnfr-1
TNF-R II is present on most cell types and is considered to play a role in cell stimulation by TNF-alpha.. TNF-R II molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha.
Applications
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilution
Western Blot: 1:10 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Form
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes the extracellular part of the mouse TNF-R II and with the soluble receptor. The reactivity of the antibodies with cellbound or soluble TNF-Receptor is not inhibited by high concentrations of mouse TNF-alpha. Crossreactivity is minimal with mouse TNF-alpha.
