Technical Data

V2121-89P4
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Serum
Applications
IHC WB
Crossreactivity
Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-VG5Q (Angiogenic Factor) (Vasculogenesis Gene on 5q, Vasculogenesis Gene on 5q Protein, hVG5Q, Angiogenic Factor VG5Q, Angiogenic Factor with G Patch and FHA Domains 1, AGGF1, FLJ10283, G Patch Domain-containing Protein 7, GPATC7, GPATCH7, HSU84971, HUS84971) (Not for Export EU)

Angiogenic factor (vasculogenesis gene on 5q), VG5Q is a critical protein for the initiation and maintenance of the vascular system. It shows strong expression in blood vessels and is secreted as vessel formation is initiated. Increased angiogenesis is a molecular pathogenic mechanism of Klippel-Trenaunay syndrome (KTS). Thus, VG5Q has been shown to be involved in KTS.

Applications
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Positive Control: Mouse skin extract
Cellular Localization: Cytoplasm
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
A synthetic peptide mapping to an epitope within residues 300-400 of the murine VG5Q protein. Epitope: Unknown
Form
As reported
Purity
Serum
Specificity
This antibody is specific for mouse VG5Q.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Tian, XL, Kadaba, R, et al. Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature. 427(6975): 640-645 (2004)
USBio References
No references available
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