Technical Data

V2124-26D
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Gene #
VISL1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-VILIP1, CT (Visinin-like Protein 1, VILIP, VLP-1,VSNL1, VISL1, Hippocalcin-like Protein 3, HLP3)

The visinin and visinin-like peptides represent a family of calcium-binding proteins that are highly expressed in the retina. Visinin has been shown to be a cone cell-specific protein with a molecular weight of 24kD. Several members of the visinin family of genes have been isolated and characterized from different species. These peptides are believed to be involved in the processes of phototransduction. The recoverin gene (RCV1) is believed to be involved in the pathophysiology of retinopathy in cancer patients.

Applications
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 123-150 in the C-terminal region of human VILIP1, Swiss/UniProt Accession: P62760.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified
Specificity
Recognizes human VILIP1. Species Crossreactivity: mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Braunewell, K.H., et al., Neuropharmacology 44(6):707-715 (2003). 2. Lin, L., et al., J. Biol. Chem. 277(44):41872-41878 (2002). 3. Spilker, C., et al., J. Neurosci. 22(17):7331-7339 (2002). 4. Bernstein, H.G., et al., Neuroreport 13(4):393-396 (2002). 5. Lin, L., et al., Biochem. Biophys. Res. Commun. 296(4):827-832 (2002).
USBio References
No references available
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