Technical Data

001027
CAS Number
1217686-68-4
Grade
Highly Purified
Molecular Formula
C42H37D8ClN6O5S2
Molecular Weight
821.48
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
ABT 737-d8
4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide-d8;

A selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines.

Form
Yellow Solid
Melting Point
148-150°C
Solubility
DMSO

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Ikegaki, N., et al.: Cancer Res., 54, 6
USBio References
No references available
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