002280
CAS Number
1219376-36-9Grade
Highly PurifiedMolecular Formula
C₅¹³C₂H₁₀N¹⁵NO₄Molecular Weight
189.14EU Commodity Code
38220090Shipping Temp
Blue IceStorage Temp
-20°C(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid-13C2,15N
D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid-13C2,15N; AMPA-13C2,15N ; |D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid-13C2,15N; γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid-13C2,15N
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.
CAS No
1219376-36-9 Unlabelled: 74341-63-2
Molecular Formula
C₅¹³C₂H₁₀N¹⁵NO₄
Form
Brown to Dark Brown Solid
Melting Point
>210°C (dec.)
Solubility
Water (Slightly)
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Krogsgaard-Larsen, et al.: Nature, 284, 64 (1980), Honore, T., et al.: J. Neurochem., 38, 173 (1982), MacDonald, J.F., et al.: Science, 253, 1132 (1991)USBio References
No references available