Artesunate-d4
Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d4; Artesunic Acid-d4
Labeled derivative of Artemisinin. Antimalarial.
Synonyms
Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d4; Artesunic Acid-d4
Molecular Formula
C₁₉H₂₄D₄O₈
Appearance
Supplied as a white solid
Solubility
Chloroform (Slightly), Methanol (Slightly)
Method for Determining Identity
Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO2;Dichloromethane: Methanol: 9:1; Visualized with AMCS and UV; Single spot, Rf=0.60
Elemental Analysis
Calculated: %C: 58.75, %H: 7.27
Normalized Intensity
d0=0.27%, d1=0.45%; d2=1.08%; d3=3.96%, d4=8.91%; d5=94.24%
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.
