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003929 Betulinic Acid CAS: 472-15-1

Specifications
References
CAS Number
472-15-1
Grade
Highly Purified
Molecular Formula
C₃₀H₄₈O₃
Molecular Weight
456.7
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Mairin; (+)-Betulinic acid; 3β-Hydroxylup-20(29)-en-28-oic Acid; Betulic Acid; Lupatic Acid; NSC 113090; β-Betulinic Acid; (3β)-3-HydroxyLup-20(29)-en-28-oic Acid

Betulinic Acid is a natural pentacyclic triterpenoid. Betulinic Acid displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity.

Synonyms
Mairin; (+)-Betulinic acid; 3β-Hydroxylup-20(29)-en-28-oic Acid; Betulic Acid; Lupatic Acid; NSC 113090; β-Betulinic Acid; (3β)-3-HydroxyLup-20(29)-en-28-oic Acid
CAS Number
472-15-1
Molecular Formula
C₃₀H₄₈O₃
Molecular Weight
456.7
Appearance
White to pale beige solid
Purity
As reported
Melting Point
>235°C (dec.)
Solubility
DMSO (Slightly), Methanol (Slightly)
Storage and Stability
Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010)
USBio References
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