Technical Data

004325
CAS Number
1392399-03-9
Grade
Highly Purified
Molecular Formula
C28H41Cl3N6O2
Molecular Weight
600.02
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
BIX 01294 Trihydrochloride
2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine Trihydrochloride;

G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor that H3K9me2 chromatin levels modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in vitro.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Kubicek, S. et al.: Mol. Cell., 25, 473 (2007); Huangfu, D et al.: Nat. Biotechnol., 26, 795 (2008); Chang, Y. et al.: Bat. Struct. Mol. Biol., 16, 312 (2009);
USBio References
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