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004331 BML-286 CAS: 294891-81-9

Specifications
References
CAS Number
294891-81-9
Grade
Highly Purified
Molecular Formula
C22H18N2O4
Molecular Weight
374.39
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
2-[[3-[(2-phenylacetyl)amino]benzoyl]amino]benzoic Acid; 2-[[3-[(phenylacetyl)amino]benzoyl]amino]benzoic Acid;

A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways.

References
Grandy, D. et al.: J. Biol. Chem., 284, 24 (2009);
USBio References
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