CDDO Imidazolide CAS 443104-02-7

Subscribe to our newsletter!

Welcome | LOG OUT

005840 CDDO Imidazolide CAS: 443104-02-7

Specifications

References

CAS Number

443104-02-7

Grade

Highly Purified

Molecular Formula

C34H43N3O3

Molecular Weight

541.72

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; CDDO-Im; RTA 403; TP 235;

CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers.

Form

Pale Yellow Solid

Melting Point

180-192°C (dec.)

Solubility

Chloroform

References

Hughes, D.T. et al.: Cancer Invest., 26, 118 (2008); Place, A.E. et al.: Clin. Cancer Res., 9, 2798 (2003); Samudio, I. et al.: J. Biol. Chem., 280, 36273 (2005);