Technical Data

005989
CAS Number
161308-35-6
Grade
Highly Purified
Molecular Formula
C19H32Na2O4
Molecular Weight
370.43
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
Chaetomellic Acid A Disodium Salt
(2Z)-2-Methyl-3-tetradecyl-2-butenedioic Acid Disodium Salt;

Chaetomellic acid A is an alkyl dicarboxylic acid isolated from the fermentation of Chaetomella acutiseta. Chaetomellic acid A has been shown to be a potent, highly specific inhibitor of RAS farnesyl protein transferase (FPTase).  The association between RAS proteins and cancer has made Chaetomellic acid A a potential chemotherapeutic agent.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Gibbs, J.B., et al.: J. Biol. Chem., 268, 7618 (1993), Tamanoi, F., et al.: Trends Biochem. Sci., 18, 349 (1993),
USBio References
No references available
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