006854
CAS Number
606-59-7Grade
Highly PurifiedMolecular Formula
C₁₄H₈N₂O₆Molecular Weight
300.22EU Commodity Code
38220090Shipping Temp
RTStorage Temp
4°CCinnabarinic Acid
2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic Acid; Cinnabaric Acid
A natural phenoxazinone derivative, Cinnabarinic acid is obtained in vitro with aid of laccase by oxidative dimerization of 3-Hydroxyanthranilic acid (a metabolite of the amino acid Trytophan). Cinnabarinic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase.
Synonyms
2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic Acid; Cinnabaric Acid
Molecular Formula
C₁₄H₈N₂O₆
NMR
Conforms to structure
Solubility
DMSO (Slightly)
Appearance
White to off-white solid
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Osiadacz, J., et al.: J. Biotechnol., 72, 141 (1999), Kumar, D., et al.: Bioorg. Med. Chem., 10, 3997 (2002), McCleland, B., et al.: Bioorg. Med. Chem. Lett., 17, 1713 (2007)USBio References
No references available