Cinnabarinic Acid CAS 606-59-7

CAS Number

606-59-7

Grade

Highly Purified

Molecular Formula

C₁₄H₈N₂O₆

Molecular Weight

300.22

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic Acid; Cinnabaric Acid

A natural phenoxazinone derivative, Cinnabarinic acid is obtained in vitro with aid of laccase by oxidative dimerization of 3-Hydroxyanthranilic acid (a metabolite of the amino acid Trytophan). Cinnabarinic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase.

Synonyms

2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic Acid; Cinnabaric Acid

CAS No

606-59-7

Molecular Formula

C₁₄H₈N₂O₆

Molecular Weight

300.22

NMR

Conforms to structure

Melting Point

>300°C

Solubility

DMSO (Slightly)

Appearance

White to off-white solid

Purity

≥95% (HPLC)

Storage and Stability

Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

Osiadacz, J., et al.: J. Biotechnol., 72, 141 (1999), Kumar, D., et al.: Bioorg. Med. Chem., 10, 3997 (2002), McCleland, B., et al.: Bioorg. Med. Chem. Lett., 17, 1713 (2007)