USBio Logo

007065 Coumaphos CAS: 56-72-4

Specifications
References
CAS Number
56-72-4
Grade
Highly Purified
MDL Number
MFCD00041820
Molecular Formula
C₁₄H₁₆ClO₅PS
Molecular Weight
362.77
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
O-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-Diethyl Ester; 3-Chloro-4-methyl-7-coumarinyl Diethyl Phosphorothioate; Asuntol; Baymix; Muscotox; Resitox

Insecticide, nematocide. Coumaphos is useful in cannabis testing kits as a component of pesticide mixes. Coumaphos is an organophosphate pesticide.1 It is converted into an oxon-containing metabolite in vivo, similar to other organophosphate pesticides, that inhibits acetylcholinesterase. It is active against adult, but not arrested stage, O. ostertagi helminths. 2 Coumaphos is toxic to A. stephensi and A. aegypti mosquitoes when applied topically, with median lethal doses of 0.002 and 0.012ug per female mosquito, respectively, but not when used as a contact insecticide.3 It is lethal to rats (LD50s = 41 and 16mg/kg for male and female rats, respectively). 4 Formulations containing coumaphos have been used to control pests in livestock.

Synonyms
O-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-Diethyl Ester; 3-Chloro-4-methyl-7-coumarinyl Diethyl Phosphorothioate; Asuntol; Baymix; Muscotox; Resitox
CAS No
56-72-4
Molecular Formula
C₁₄H₁₆ClO₅PS
Molecular Weight
362.77
Purity
≥95%
Melting Point
93-95ºC
Solubility
DMSO (Slightly), Methanol (Slightly)
TLC Conditions
SiO2; Hexanes : Ethyl Acetate = 9 : 1; Visualized with UV, AMCS, and KMnO4; Single Spot, Rf = 0.30.
Method for Determining Identity
Proton NMR, 31P NMR, and MS conform to structure.
Elemental Analysis
Calculated: %C: 46.35, %H: 4.45
Appearance
Pale red to tan solid
Storage and Stability
Store at -20°C. Hygroscopic, Under Inert Atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Guo, J.-X., Wu, J.J.-Q., Wight, J.B., et al. Mechanistic insight into acetylcholinesterase inhibition and acute toxicity of organophosphorus compounds: A molecular modeling study. Chem. Res. Toxicol. 19(2):209-216 (2006). 2. Prichard,R.K.Anthelminticsandcontrol.Vet.Parasitol.27(1-2):97-109(1988). 3. Hadaway, A.B. and Barlow, F. The toxicity of some organophosphorus compounds to adult Anopheles stephensi. Bull. World Health Organ. 28(1):55-61 (1963). 4 Gaines, T.B. Acute toxicity of pesticides. Toxicol. Appl. Pharmacol. 14(3):515-534 (1969). 5. Krueger, et al.: J. Agric. Food Chem., 7:183 (1959) 6. Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14:515 (1969)
USBio References
No references available
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
  • Contact Us

    Visit our technical library or contact our support staff to answer your questions.

    Telephone:
    1-800-520-3011

    Library | Contact

    Distributors

    For customers outside of the United States, please use one of our many distributors.

    View Distributors

    Payment Methods

    We accept the following payment methods as well as pay-by-invoice.

    MasterCard Visa PayPal
    © 2023-2024 United States Biological - All Rights Reserved