CP-91149

007096

CAS Number

186392-40-5

Grade

Highly Purified

Molecular Formula

C21H22ClN3O3

Molecular Weight

399.87

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

5-Chloro-N-[(1S,2R)-3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; [R-(R,S)]-5-Chloro-N-[3-(dimethylamino)-2-hydroxy-3-oxo-|1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; CP 91149;

Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression. Antitumor agent.

Form

White Solid

Melting Point

190-192°C

Solubility

Chloroform, DMSO

Pfizer Compound

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Newgard, C., et al.: J. Biol. Chem., 263, 3850 (1988), Ignacio, P., et al.: Brain Res., 529, 42 (1990), Oikonomakos, N., et al.: J. Biol. Chem., 275, 34566 (2000), Pedersen, B., et al.: J. Biol. Chem., 275, 27753 (2000),

USBio References

No references available

Technical Data