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007096 CP-91149 CAS: 186392-40-5

Specifications
References
CAS Number
186392-40-5
Grade
Highly Purified
Molecular Formula
C21H22ClN3O3
Molecular Weight
399.87
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
5-Chloro-N-[(1S,2R)-3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; [R-(R*,S*)]-5-Chloro-N-[3-(dimethylamino)-2-hydroxy-3-oxo-|1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; CP 91149;

Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression. Antitumor agent.

Form
White Solid
Melting Point
190-192°C
Solubility
Chloroform, DMSO
Pfizer Compound
References
Newgard, C., et al.: J. Biol. Chem., 263, 3850 (1988), Ignacio, P., et al.: Brain Res., 529, 42 (1990), Oikonomakos, N., et al.: J. Biol. Chem., 275, 34566 (2000), Pedersen, B., et al.: J. Biol. Chem., 275, 27753 (2000),
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