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008818 Dexamethasone-d5 CAS: 358731-91-6

Specifications
References
CAS Number
358731-91-6
Grade
Highly Purified
Molecular Formula
C22H24D5FO5
Molecular Weight
397.49
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-pregna-1,4-diene-3,20-dione-d5; 16α-Methyl-9α-fluoroprednisolone-d5; Aeroseb-Dex-d5; Corson-d5; Cortisumman-d5; Decacort-d5; Decaderm-d5; Decadron-d5; Decalix-d5; Decasone-d5; Dekacort-d5

A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Synonyms
(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-pregna-1,4-diene-3,20-dione-d5; 16α-Methyl-9α-fluoroprednisolone-d5; Aeroseb-Dex-d5; Corson-d5; Cortisumman-d5; Decacort-d5; Decaderm-d5; Decadron-d5; Decalix-d5; Decasone-d5; Dekacort-d5
CAS No
358731-91-6
Molecular Formula
C22H24D5FO5
Molecular Weight
397.49
Appearance
Off-white to pale yellow solid
Purity
Chemical Purity: ≥98%; Isotopic Purity: ≥96%
1H NMR (DMSO-d6)
Conforms to reference
19F NMR (DMSO-d6)
Conforms to reference
MS
Conforms to reference
TLC Conditions
SiO2; Dichloromethane : Methanol = 9 : 1; Visualized with UV and AMCS; Single Spot, Rf = 0.40
Melting Point
>240°C (dec.)
Solubility
Dioxane (Slightly, Sonicated), DMSO (Slightly), Methanol (Very Slightly, Heated)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)
USBio References
No references available
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