Diclofenamide

009313

CAS Number

120-97-8

Grade

Highly Purified

Molecular Formula

C6H6Cl2N2O4S2

Molecular Weight

305.16

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

1,3-Disulfamoyl-4,5-dichlorobenzene; 1,3-Disulfamyl-4,5-dichlorobenzene; 3,4-Dichloro-5-sulfamylbenzenesulfonamide; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-m-benzenedisulfonamide; Antidrasi; CB 8000; Daramide; Daranide; Dichlofenamide; Dichlorophenamide; Dichlorphenamide; Diclofenamid; Glaucol; Oratrol;

Diclofenamide is a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).

Form

Off-White Solid

Melting Point

237-240°C

Solubility

Chloroform, Methanol

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010); Tawil, R. et al.: Ann. Neurol., 47, 46 (2000); Casey, J. et al.: J. Med. Chem., 47, 2337 (2004);

USBio References

No references available

Technical Data