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010967 Doxycycline Hyclate CAS: 24390-14-5

Specifications
References
CAS Number
24390-14-5
Grade
Highly Purified
Molecular Formula
C22H24N2O8·HCl·0.5C2H6O·0.5H2O
Molecular Weight
512.94
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Doxycycline hydrochloride hemiethanolate hemihydrate; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hyclate

A synthetic derivative of oxytetracycline. Acts as a broad spectrum antibiotic and matrix metallo-proteinases (MMP) inhibitor. Useful in studies involving wound healing and tissue remodeling.

Synonyms
Doxycycline hydrochloride hemiethanolate hemihydrate; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hyclate
CAS Number
24390-14-5
Molecular Formula
C22H24N2O8·HCl·0.5C2H6O·0.5H2O
Molecular Weight
512.94
Appearance
Yellow crystalline powder
Purity
95-102% (anhydrous and ethanol free)
Melting Point
206-209°C (dec.)
Water
1.4-2.8%
Ethanol
4-6%
Specific Optical Rotation
As reported
Solubility
DMSO (~100mM) or H2O (~100mM), Methanol
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
1. Fabre, et al.: Chemotherapia, 11, 73 (1966), 2. Goldenthal, et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), 3. Polson, A.M., et al.: J. Periodontol., 68, 110 (1997).
USBio References
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