Technical Data

011406
CAS Number
438-67-5
Grade
Highly Purified
MDL Number
MFCD00070035
Molecular Formula
C18H21NaO5S
Molecular Weight
372.41
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Estrone 3-Sulfate Sodium Salt
3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt; Estra-1,3,5(10)-trien-17-one 3-(Sulfooxy) Sodium Salt; Estrone Sulfate Sodium Salt; Conestoral; Estrone Sodium Sulfate; Morestin; NSC 18313; Sodium Estrone-3-sulfate

Estrogen used in hormone replacement therapy.

Synonyms
3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt; Estra-1,3,5(10)-trien-17-one 3-(Sulfooxy) Sodium Salt; Estrone Sulfate Sodium Salt; Conestoral; Estrone Sodium Sulfate; Morestin; NSC 18313; Sodium Estrone-3-sulfate
CAS No
438-67-5
Molecular Formula
C18H21NaO5S
Molecular Weight
372.41
Appearance
White solid
Purity
≥95%
Melting Point
270-275˚C
Solubility
Methanol: ~20mg/ml, clear, colorless to faintly yellow
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Kannel, W., et al.: J. Clin. Epidemiol., 44, 183 (1991)|2. Raisz, L., et al.: J. Clin. Endocrinol. Metab., 81, 37|3. Nakamura Y, et al. Steroid sulfatase and estrogen sulfotransferase in the atherosclerotic human aorta. Am J Pathol. 2003;163(4):1329-1339.|4. Duncan L, et al. Inhibition of estrone sulfatase activity by estrone-3-methylthiophosphonate: a potential therapeutic agent in breast cancer. Cancer Res. 1993;53(2):298-303.|4. Karakus E, et al. Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6). Front Pharmacol. 2018;9:941. Published 2018 Aug 21.
USBio References
No references available
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