Eurycomanone CAS 84633-29-4

CAS Number

84633-29-4

Grade

Highly Purified

Molecular Formula

C₂₀H₂₄O₉

Molecular Weight

408.4

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

1,20-Epoxy-1,11,12,14,15-pentahydroxy-(1β,11β,12α,15β)-Picrasa-3,13(21)-diene-2,16-dione; NSC 339187; Pasakbumin A

Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.

CAS No

84633-29-4

Molecular Formula

C₂₀H₂₄O₉

Melting Point

>220°C (dec.)

Solubility

DMSO (Slightly), Pyridine (Slightly, Sonicated)

Storage and Stability

Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

Wong, P.F., et al.: Phytomed., 19, 138 (2012); Nurkhasanah, M., et al., Medunion Press., 4, 109 (2008); Zakaria, Y., et al.: Cancer Cell Intern., 9, (2009);