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012783 Gimeracil CAS: 103766-25-2

Specifications
References
CAS Number
103766-25-2
Grade
Highly Purified
Molecular Formula
C5H4ClNO2
Molecular Weight
145.54
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
5-Chloro-4-hydroxy-2(1H)-pyridinone; 5-Chloro-2,4-dihydroxypyridine; 5-Chloro-4-hydroxy-2-pyridone; Gimestat; CDHP

Gimeracil is an antitumor agent. Gimeracil is a potent inhibitor of dihydropyrimidine dehydrogenase (DPD).

Form
Off-White Solid
Melting Point
>270°C (dec.)
Solubility
DMSO
References
Shirasaka, T., et al.: Cancer Res., 56, 2602 (1996), Patt, Y., et al.: J. Clin. Oncol., 22, 271 (2004), Shirao, K., et al.: Cancer, 100, 2355 (2004), Kelly, H., et al.: J. Clin. Oncol., 23, 4553(2005),
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