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013524 5-Hydroxy Buspirone CAS: 105496-33-1

Specifications
References
CAS Number
105496-33-1
Grade
Highly Purified
Molecular Formula
C₂₁H₃₁N₅O₃
Molecular Weight
401.5
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
8-[4-[4-(5-Hydroxy-2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione

A metabolite of Buspirone.

Synonyms
8-[4-[4-(5-Hydroxy-2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione
CAS No
105496-33-1
Molecular Formula
C₂₁H₃₁N₅O₃
Molecular Weight
401.5
Appearance
Supplied as an off-white solid
Purity
≥98%
Melting Point
48-53°C
Solubility
Methanol
Atmosphere
Inert gas
Method for Determining Identity
Proton NMR (CD3OD) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO:2; Dichloromethane: Methanol: 4:1; Visualized with UV and AMCS; Single spot, Rf=0.60
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmosphere.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Rabiner, E., et al.: Nucl. Med. Biol., 27, 509 (2000), 2. Zhu, M., et al.: Drug Metab. Dispos., 33, 500 (2005), 3. Dockens, R., et al.: J. Clin. Pharmacol., 46, 1308 (2006). 4. Wong, H., et al.: Drug Metab. Dispos., 35, 1387 (2007).
USBio References
No references available
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