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014975 Isobarbituric Acid CAS: 496-76-4

Specifications
References
CAS Number
496-76-4
Grade
Highly Purified
Molecular Formula
C4H4N2O3
Molecular Weight
128.09
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
2,4,5-Trihydroxypyrimidine; Dihydro-2,4,5(3H)-pyrimidinetrione; 5-Hydroxyuracil; NSC 95958; ||

A 5-hydroxy derivative of the nucleobase Uracil and an isomer of Barbituric Acid. Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin

References
Varatharasa T. et al.: Chem. Comm., 3, 400 (2005); Jaruga, P. et al.: Nucleic Acid Res., 24, 1389 (1996); Rodriguez, H. et al.: Adv. Exp. Med. Biol., 534, 129 (2003);
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