015219
CAS Number
579-56-6Grade
Highly PurifiedMolecular Formula
C18H24ClNO3Molecular Weight
337.84EU Commodity Code
38220090Shipping Temp
RTStorage Temp
4°CIsoxsuprine Hydrochloride
4-Hydroxy-α-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]benzenemethanol Hydrochloride; p-Hydroxy-α-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]benzyl Alcohol Hydrochloride; p-Hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine Hydrochloride; 1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 Hydrochloride; Dilavase; Divadilan; Duvadilan; Duviculine; Isolait; Isoxsuprine Hydrochloride; Navilox; Suprilent; Suprox SR; Tidilan; Vadosilan; Vasodilan; Vasoplex; Vasotran;
A vasilodator drug. It is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. It has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that ut may be useful as a as a tocolytic agent in the treatment of preterm labour.
Solubility
DMSO, Methanol
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Erkert, R.S. et al.: J. Vet. Pharmacol. Therap., 25, 81 (2002); Giorgino, F.L. et al.: Arzneim. Forsch., 60, 415 (2010);USBio References
No references available