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015869 Medroxy Progesterone-d3 CAS: 162462-69-3

Specifications
References
CAS Number
162462-69-3
Grade
Highly Purified
Molecular Formula
C₂₂H₂₉D₃O₃
Molecular Weight
347.51
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
6α-17-Hydroxy-6-(methyl-d3)-pregn-4-ene-3,20-dione; 17α-Hydroxy-6α-methyl-d3)|-progesterone; 17-Hydroxy-6α-(methyl-d3)pregn-4-ene-3,20-dione; NSC 27408-d3

Labeled Medroxyprogesterone, an orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.

Synonyms
6α-17-Hydroxy-6-(methyl-d3)-pregn-4-ene-3,20-dione; 17α-Hydroxy-6α-methyl-d3) -progesterone; 17-Hydroxy-6α-(methyl-d3)pregn-4-ene-3,20-dione; NSC 27408-d3
CAS No
162462-69-3 Unlabeled: 520-85-4
Molecular Formula
C₂₂H₂₉D₃O₃
Molecular Weight
347.51
Purity
≥95%
Appearance
Off-white to grey solid
Melting Point
As reported
Solubility
Chloroform (Very Slightly)
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO2; Ethyl Acetate: Hexanes 1:1 Visualized with UV and AMCS; Single spot, Rf=0.45
Elemental Analysis
Calculated: %C: 76.04, %H: 9.29
Normalized Intensity
As reported
Specific Rotation
As reported
Storage and Stability
Store at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Pan, Q., et al.: Mol. Hum. Reprod., 13, 797 (2007). 2. Matsson, P., et al.: J. Pharmacol. Exp. Ther., 323, 19 (2007). 3. Jukosky, J.A., et al.: Bull. Environ. Contam. Toxicol., 81, 230 (2008). 4. Cherkasov, A., et al.: J. Med. Chem., 51, 2047 (2008)
USBio References
No references available
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